Treatments for type 1 diabetes



Treatment for type 1 diabetes is a lifelong commitment to: Take insulin, Exercise regularly and maintain a healthy weight, Eating healthy food, Glucose monitoring. The goal is to keep your blood sugar in the blood as close to normal as possible to delay or prevent complications. Although there are exceptions, generally, the goal is to keep your sugar levels in the blood during the day between 80 and 120 mg / dL (4.4 to 6.7 mmol / L) and your numbers lie between 100 and 140 mg / dL (5.6 to 7.8 mmol / L). If managing your diabetes seems overwhelming, take it one day at a time. And do not forget that you are not alone. You will work closely with your diabetes care team - doctor, diabetes educator and dietitian - to keep your levels of blood sugar as close to normal as possible.

 Anyone who has type 1 diabetes needs insulin therapy to survive. Types of insulin are many and include: Rapid-acting insulin Acting insulin Intermediate options Examples are insulin (Humulin R, Novolin R, other), NPH insulin (Humulin N, Novolin N), insulin lispro (Humalog), insulin aspart (NovoLog), insulin glargine ( Lantus) and insulin detemir (Levemir). Depending on your needs, your doctor may prescribe a mixture of insulin types to use throughout both day and night. An inhaled insulin (Exubera) was previously available, but the manufacturer stopped selling the drug because too few people used it. Since it was removed from the market, the drug was associated with an increase in lung cancer among people with a history of smoking. However, because the number of additional cases of lung cancer is so small, it is not clear whether there is a link with the drug. If you used Exubera and history of smoking, discuss these concerns with your doctor. Options for injection of insulin in your body currently include injection and infusion insulin pump. Insulin cannot be taken orally to lower blood sugar because stomach enzymes interfere with insulin action. Insulin injections can be done using: A fine needle and syringe. An insulin pen is a device that resembles a pen ink, except that the cartridge is filled with insulin. An insulin pump is a device the size of a cell phone worn on the outside of your body. A tube connects a reservoir of insulin to a catheter which is inserted under the skin of the abdomen. There is also a wireless pump option is available in most areas. You wear a bucket filled with insulin in your body which has a tiny catheter that is inserted under the skin. Clove of insulin can be worn on the abdomen, lower back, or a leg or an arm. Programming is performed with a wireless device that communicates with the container. Whatever pump you use, it is programmed to dispense specific amounts of rapid-acting insulin automatically. This stable dose of insulin is known as base flow, and replaces the long-acting insulin you use.

When you eat, you can program the pump with the amount of carbohydrates you eat and your blood sugar in progress, and it will give you what is called a "bolus" dose of insulin to cover your meals and correct if your blood sugar is high. Some research has shown an insulin pump to be more effective in controlling sugar levels in the blood than the injections. Oral medications are sometimes prescribed as well, such as: Pramlintide (Symlin). An injection of this drug before you eat can slow the passage of food in the stomach to reduce sharp rise in blood sugar that occurs after meals. Antihypertensive: Even if you do not have high blood pressure, your doctor may prescribe medicines known as angiotensin converting enzyme (ACE) receptor blockers or angiotensin II inhibitors (ARBs), because these medications can help keep your kidneys healthy in addition to lowering blood pressure. It is recommended that people with diabetes have blood pressure less than 130/80 millimeters of mercury (mmHg). Cholesterol: As antihypertensive, your doctor can not wait until your cholesterol is high before he or she prescribes cholesterol, called statins. Guidelines are more aggressive cholesterol for people with diabetes because of the high risk of heart disease. The American Diabetes Association recommends that low-density lipoprotein (LDL, or "bad") cholesterol below 100 mg / dL (2.6 mmol / L) and lipoprotein hautoudensité (HDL, or "good") rate Cholesterol is more than 50 mg / dL (1.3 mmol / L). Triglycerides, another type of fat in the blood are IDMG / dL quandmmol / Lont least 150 mg / dL (1.7 mmol / L). A healthy diet and counting carbohydrates, Physical activity, Glucose monitoring, Situation concerns- Experimental Treatments do well.

 Pancreas transplant: With a successful pancreas transplant, you no longer need insulin. Pancreas transplant but are not always successful - and the procedure has serious risks. You would need a powerful immunosuppressive life drugs to prevent organ rejection. These drugs can have serious side effects, including an increased risk of infection and organ damage. Because side effects may be more dangerous than diabetes, pancreas transplants are usually reserved for those who have very difficult to control diabetes. Islet cell transplantation: Researchers are experimenting with transplantation of islets of Langerhans, which provides new insulin-producing cells from a donor pancreas. Although this experimental procedure has encountered problems in the past, new techniques and better drugs to prevent rejection of islet cells can improve their chances of future success.

However, islet transplantation still requires the use of immunosuppressive drugs, and just as he did with his own natural islet cells, the body destroys the cells of transplanted islets often taking the time to insulin short duration. In addition, sufficient islet cells are not available for this treatment to become more widespread. Stem cell transplantation: In a 2007 study in Brazil, a small number of people newly diagnosed with type 1 diabetes were able to stop using insulin after being treated with stem cells made from their own blood. Although stem cell transplants - which involves stopping the immune system, then build it again - can be risky, the technique could one day offer an additional treatment option for type 1 diabetes.

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